Vitamin C is an essential micronutrient, a powerful antioxidant and a cofactor of enzymes for gene regulation. It contributes to the immune defense by supporting the various cellular functions of the innate and acquired immune response. Vitamin C deficiency leads to impaired immunity and greater susceptibility to infections. Vitamin C supplementation can prevent and treat respiratory and systemic infections. In addition to the known effects of vitamin C deficiency (fatigue, exhaustion, sensitivity and tendency for bleeding gums) can lead to the development of osteoporosis in patients with inflammatory bowel disease can modify the composition of the intestinal microbiota as well, which plays a key role in the pathogenesis of inflammation with nonalcoholic fatty liver disease patients. Oral ingestion of large-dose vitamin C supplements results in limited intestinal vitamin C absorption with excess ascorbic acid remaining in the gut lumen where it can potentially exert beneficial effects both on the intestinal cells and microbiota composition and function.

Zinc is an important trace element of the human body, which is crucial for the growth, development and function of the immune system essential for natural barriers preservation in tissues, such as the respiratory epithelium, preventing the entry of pathogens. It has a direct antiviral effect. Zinc deficiency increases the risk of infectious, autoimmune, cardiovascular and malignant diseases, as well as infertility, infectious diseases, especially respiratory infections, HIV infections and hepatitis C virus.
Oral vitamin supplementation can cause nausea and stomach pain, especially on an empty stomach. Using vitamin C and Zinc supplements in the form of a spray is highly recommended as a safe and reasonable consumption, which avoids these side effects and provides basic body functions.